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Anastrozole Arimidex therapy for positive breast cancer

TopSteroid593
using substantial amounts of aromatizing steroids
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$20.00
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$16.00
50-99
$12.00
100-499
$11.00
500-999
$10.00
1000+
$9.50
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  • Description
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Anastrozole
Alias: Arimidex
CAS No: 120511-73-1
MF: C17H19N5
MW: 293.37


Melt point: 81-82℃
Purity: 98%
Appearance: white powder.

Applications:
The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.
The trial suggested that anastrozole is the preferred medical therapy for postmenopausal women with localized estrogen receptor (ER) positive breast cancer.

Specifications:
Items Standard Results
Description White crystalline powder Complies
Identification IR
HPLC
Reactive
Conform with standard IR
Conform with standard HPLC
Conform
Solubility Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile Complies
Total Impurity max.0.5% 0.18%
Total Unspecified Impurity max. 0.2% 0.08%
Individual unspecified impurlty max. 0.1% 0.05%
Related compound B max. 0.2% 0.07%
Related compound C max. 0.2% 0.04%
Related compound D max. 0.1% 0.05%
Related compound E max. 0.1% 0.06%
Limit of cyclohexane max. 0.08% ND
Limit of ethylacetate max. 0.1% 0.07%
Melting point 81.0~84.0℃ 82.5~83.2℃
Water max. 0.3% 0.21%
Residue on ignition max. 0.1% 0.07%
Heavy Metals max.0.001% Complies
Assay(HPLC) 98.0%~102.0% 99.8%
Storage Cool and dry
Conclusion It complies to USP32 .
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