Exemestane
Alias: Aromasin ; Exemestan
CAS NO: 107868-30-4
MF: C20H24O2
MW: 296.4
Purity: 99%
Appearance: white solid powder.
Applications:
the third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.
Specifications:
TEST ITEMS |
SPECIFICATION |
RESULTS |
Description |
: White Crystalline Powder |
White Powder |
Identification |
: Positive |
Positive |
Assay(by HPLC) |
: 98.0~102.0% |
98.64% |
Absorbance(E1cm) |
: 465~495 |
482.5 |
Melting Point |
: 191~195°C |
193.5~195.0°C |
Loss On Drying |
: 0.5%max |
0.19% |
Specific Rotation |
: +288°~ +298° |
+290.2° |
Residue On Ignition |
: 0.1%max |
0.03% |
Related Substances |
: Total:1.5%max |
<1.3% |
|
Single:0.5%max |
<0.4% |
Residue Solvents |
: 0.2%max |
0.10% |
Heavy Metals |
: 20PPm max |
<10PPm |
|
|
|
Conclusion |
The specification conform with enterprise standard. |